Robotic Platforms

Different robotic arm choices are available for robotic platform automation. Our software solutions allow the integration of one or more arms on the same platform. The proposed solutions are based on the methods to be executed, the number of devices to connect, and the constraints of the room hosting the solution.

To support users of various High-Throughput Screening (HTS) robotic platforms, dedicated compound management platforms provide the flexibility, robustness, and throughput required for logistics. Whether delivering assay-ready microplates or managing its own screening, we handle microplates in 96, 384, and 1536 formats, as well as microtubes. Various pipetting modes and distributions are available to handle volumes from 20 nL to 1000 µL.

The implementation of High Content Screening (HCS) or High Content Analysis (HCA) allows for accelerated throughput with this type of reader through automation. The automated approach to using HCS or HCA readers must take into account many factors since handling live cells requires reproducible results to be exploitable. This is a relatively new approach, but we have already completed several integrations of this technology combined with high-throughput challenges.

The collaboration between Bruker Daltonics and Analytik Jena aims to offer a comprehensive solution for µHTS.

Jena (Germany) / Washington, February 7, 2017 – Analytik Jena partnered with Bruker Daltonics to accelerate two key steps: automatic sample preparation in Ultra High Throughput Screening (µHTS) for Matrix-Assisted Laser Desorption/Ionization (MALDI) and the integration with label-free Time Of Flight (TOF) spectrometry, ensuring pharmaceutical screenings in µHTS.
The collaboration was showcased at the international SLAS 2017 conference in Washington, highlighting innovations in automation and screening processes.

With Analytik Jena’s Cybio® Well Vario automated pipettor, used for MALDI plate preparation, parallel processes allow new speeds of analysis. Bruker Daltonics' RapifleX MALDI PharmaPulse, the fastest mass spectrometer on the market, is used for plate analysis.

Less than 10 minutes for a 1536-well microplate
Sample preparation and MALDI target spotting are timed to produce plates on-demand without interruption for analysis in the RapifleX MALDI PharmaPulse. The complete preparation time for a 1536-well plate by the pipettor takes less than 10 minutes. Over one million tests are now possible per week.

For over 25 years in HTS laboratories, we have offered a wide range of configurations for pharmaceutical or viral compound screening. Whether conducting tests on bioactive molecules or interaction assays through in vitro or cell-based enzymatic assays (binding assays, HTRF, enzymatic assays, soluble factor release, toxicity, etc.), we offer personalized studies on request.

The implementation of metabolic engineering involves a wide variety of combinations that only an automated approach can reliably and quickly achieve. Whether you wish to modify the genome of microorganisms and process thousands of genetic modifications or characterize your genetic constructs, various solutions are available to successfully conduct your synthetic biology projects.